Share on Facebook yohimbine Medical Encyclopedia Wikipedia yo·him·bine (yō-hĭm′bēn′) n. An alkaloid, C21H26N2O3, that is derived from the bark of a tree,Pausinystalia johimbe,and is an alpha-blocker drug used in the form of its hydrochloride as a mydriatic, a treatment for erec...
Yohimbineis an extract from the bark of the Yohim tree. As a pharmacological agent, this centrally active alpha-2 antagonist has been prescribed for over 70 years and was a popular choice forEDbefore the advent of PDE-5 inhibitors[66]. A meta-analysis of sevenrandomized controlled trialsfound...
Medianintervals for sedation return, in minutes,were significantly lower in amitraz-intoxi- cated cats treated with either yohimbine or atipamezole. Yohimbine and atipamezole were very effective in the treatment ofamitraz intoxication, although atipamezole was more effective in reversal of arrhyth...
Both ingredients have a history of use in traditional African medicine but yohimbine has the best credentials. It gets a lot of attention for its longstanding reputation as an aphrodisiac and, to this day, is commonly used as a natural treatment for erectile dysfunction (ED). Yohimbine extracts ...
Divalent cations at millimolar concentrations decreased the [ 3 H]-YOH binding: IC 50 values were about 6.0, 6.8 and 0.3 mM for Ca 2+ , Mg 2+ and Mn 2+ respectively. The maximal number of [ 3 H]-YOH binding sites in the cortex was close to that labelled by the agonist [ 3 H]...
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Erectile dysfunction (ED).There is evidence that yohimbine, the active ingredient of yohimbe, can be helpful for ED. Some herbalists suggest that the yohimbe bark actually works better than the yohimbine ingredient alone. However, so far yohimbe bark has not been evaluated in research studies. ...
The [ 3 H]-YOH binding sites exhibited α 2 -adrenergic receptor specificity; the order of potency for the antagonists was rauwolscine > yohimbine prazosin > corynanthine. For the agonists, the order was: oxymetazoline > clonidine > ()-adrenaline > ()-noradrenaline ()-phenylephrine. Agonists...
The present results are consistent with such an interpretation and suggest that yohimbine may be of limited value as a research tool for the study of anxiety. REFERENCES CHARNEY, D. S., HENINGER, G. S., '" REDMOND, D. E. (1983) . Yohimbine induced anxiety and increased noradrenergic ...
Prevention of ischemic ventricular tachycardia of Purkinje origin: role for α2-adrenoceptors in Purkinje? Recent studies have shown the presence of postjunctional alpha(2)-adrenergic receptors on canine Purkinje fibers but not muscle cells. Stimulation of these... DO Arnar,DZ Xing,HC Lee,... ...